Clinical Safety and Efficacy Testing
MD Lash Factor ® Eyelash Conditioner
Ocular & Systemic Safety Profile
- Ocular Tolerance: In a four-week evaluation of 35 subjects under ophthalmologist supervision, no potential for eliciting ophthalmic irritation was demonstrated under study conditions. The panel included contact lens wearers, non-wearers and subjects with self-assessed sensitive eyes.
- Ophthalmic Examination: No clinically significant change in visual acuity, corneal health or tear film was observed over the four-week study.
- Intraocular Pressure (IOP): No clinically significant change in intraocular pressure was observed under study conditions.
- Toxicological Assays: Confirmed Non-Mutagenic (Ames Assay), Non-Cytotoxic (Agarose Overlay), and Non-Sensitizing (LLNA - Murine Local Lymph Node Assay).
EU Cosmetic Product Safety Report (Regulation (EC) No. 1223/2009):
Independent safety assessment. Regulation (EC) No. 1223/2009 replaced Council Directive 76/768/EEC in July 2013. Reviewer Dr. John Hopkins (BSc. PhD. MSB. C Biol.) evaluated:
Independent safety assessment. Regulation (EC) No. 1223/2009 replaced Council Directive 76/768/EEC in July 2013. Reviewer Dr. John Hopkins (BSc. PhD. MSB. C Biol.) evaluated:
- Toxicological profiles and chemical structures of each ingredient.
- Specific exposure characteristics for the intended application area.
- Absence of prohibited, restricted, or improperly characterized substances.
MD® Brow
- Self-Assessed Appearance: 78% of participants in a 56-day consumer-use study agreed their eyebrows seemed thicker. Self-assessment questionnaire responses; density was not measured.
- Condition & Texture: In the same self-assessment questionnaire, 87% agreed their eyebrows seemed healthier and better hydrated, and 78% agreed their brows seemed better conditioned.
- Tolerability: 87% of participants reported no irritation of the eyes or skin during the study.
MD® Hair Restoration & Nutri Hair
Hair Restoration System (Activator & Energizer)
- Hair Density: In a 17-week independent study at Spincontrol North America Inc., hair density was assessed by photographic analysis.
- Appearance of Hair: Alongside the instrumental assessment, 71% of subjects reported an improvement in the appearance of their hair.
- Subject Satisfaction: 75% of participants said they would recommend the product.
MD Nutri Hair Supplements
- Office-Based Review: 30-day observational review of 30 subjects confirmed high compliance and early improvements in hair strength and quality.
- Bioavailability Confirmation: Independent analytical testing (using data-file response ratios and ISTD comparisons) verified the stability and bioavailability of core active ingredients, ensuring effective nutrient delivery.
MD® Scalp Essential
- Scalp Health: Demonstrated marked decrease in visible flaking and reduction in excess sebum (oil) production.
- Irritation Relief: Significant clinical reduction in self-reported scalp itching and redness.
- Dermatological Safety: In a 50-subject repeat insult patch test, no sensitisation was observed under study conditions.
Clinical Summary Matrix
| Product | Primary Benefit | Key Safety Milestone |
|---|---|---|
| MD Lash Factor | Enhanced Lash Appearance | Ophthalmologist Tested; Ames/LLNA Negative |
| MD Brow | 78% Agreed Brows Seemed Thicker (self-assessed) | No Irritation Reported by 87% of Participants |
| MD Hair System | Hair Density Assessed by Photographic Analysis; 71% Reported Improved Hair Appearance | 75% Would Recommend |
| MD Scalp Essential | Controls Flaking & Oil | No Sensitisation Observed (50-Subject RIPT) |
| MD Nutri Hair | Hair Quality & Strength | Bioavailability Verified Active Ingredients |
Regulatory Note: These findings are derived from independent clinical trials, toxicological assessments, and professional observational reviews. MD® products are cosmetic in nature and are intended to improve the appearance of the hair, lashes, and brows. They are not intended to diagnose, treat, cure, or prevent any medical condition or disease.
